The National Institutes of Health (NIH) recently announced that patients are now enrolling in an early-stage clinical trial to test a universal flu vaccine based on messenger RNA technology.
Scientists hope the vaccine will protect against a wide variety of flu strains and provide long-term immunity so people do not have to receive a shot every year.’s widely used Covid vaccines. NIH played a crucial role in developing the mRNA platform used by Moderna.
The universal flu vaccine trial will enroll up to 50 healthy people ages 18 through 49 to test whether the experimental shot is safe and produces an immune response, according to NIH. …During Phase 1 of the trial, enrollees will be monitored for a year, and will receive different dosage levels, with a portion of participants used as a control group with the current vaccine. Researchers will study the vaccine’s safety and immune response, including how it holds up if the virus changes. Based off those results, it could be expanded to include other age groups.
The study, published in Nature, was a landmark in the yearslong movement to make cancer vaccines tailored to the tumors of individual patients.
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